Japanese woman is first recipient of next-generation stem cells

A Japanese woman in her 70s is the world’s first recipient of cells derived from induced pluripotent stem cells, a technology that promises to work wonders and has the scientific community excited about the perspectives. Surgeons working on the case created the retinal tissue after reverting the patient’s own cells to ‘pluripotent’ state. If you’d like to benefit from stem cells, but

Chimeric organ harvesting: growing human organs inside pigs

Sure to raise a slew of controversy and debate, researchers in Japan are currently investigating the possibility of growing human organs, like kidneys, livers or even hearts, inside pigs. A real life chimeric tale, as if spawned from the Island of Dr. Moreau. The challenges are numerous though, both technical (we’re talking about growing human organs in a foreign host),

First functioning lung and airway cells grown from human stem cells

Biotechnology is growing fast and the findings researchers are making the field are nothing short of breathtaking. Previously, ZME Science reported in the past few years alone a series of milestone premiers: the first bioengineered kidney and 3-D human kidney cells, the  first functioning blood vessels, the first teeth-like structures, a bioengineered heart that beats on its own and many more. All of

Kidney 3-d structures from human stem cells made for the first time

Scientists at the   Salk Institute for Biological Studies have for the first time coaxed   human stem cells into forming three-dimensional cellular structures similar to those found in our kidneys. The breakthrough could provide a valuable footing for upcoming work that might eventually lead to fully functioning lab-grown kidneys, based on patients’ own cells for bio-compatibility. In its current stage, lab-grown kidney-like

Scientists grow brain-like tissue in petri dish

Most medical research looking to identify the mechanisms of a disease or test treatments rely on animal models. While very useful, mice for instance (a favorite lab pet for researchers) do not have nearly the same brain structure or genes as humans. Even if some genes and proteins scientists target are the same both in mice and humans, it will

Scientists engineer heart in the lab that beats on its own

Regenerative medicine has come a long way, and while important strides forward have been made, scientists are still toiling with ways to completely grow organs in labs. There are millions of people worldwide suffering from afflictions to organs like the liver, lungs or heart – for many of them a transplant is they’re only chance at living a normal life

Researchers grow teeth-like structure using stem cells from urine

A new study performed by scientists in China has further elevated stem cell research after they successfully grew teeth-like structures using cells derived from an unlikely source: urine. Eventually, they hope that human stem cells could provide the basis for a tooth bud that could be transplanted into the jaw of the patient. Some of you might find it weird that

Scientists create functional blood vessels from adult stem cells

Researchers at Harvard-affiliated Massachusetts General Hospital (MGH) have successfully grown and inserted functional blood vessels into animal models after they  used vascular precursor cells derived from human induced pluripotent stem cells (iPSCs). These blood vessels lasted for as long as nine months, much longer than any previous attempt, making the Harvard researchers’ efforts seem extremely promising. Patients suffering from damaged blood vessels,

3D printing stem cells could be used one day to ‘manufacture’ organs

We’re only in the early days of 3-D printing, but even now the breakthroughs made using such technology are most impressive like the genuine possibility of printing spare parts in space for the ISS, creating objects of great details on the nanoscale or even artificial muscles made using a 3-D printer. What’s fabulous though is that 3-D printing is developing

New method allows large molecules to get squeezed through cell membranes

A group of researchers at MIT have devised a new method for infiltrating cells with large molecules such as nanoparticles or proteins that is a lot more non-intrusive and doesn’t damage the cell. Imaging target cells or growing more stable stem cells might thus be possible with this method. Every cell has a membrane, which is put to great use

Massive database of of 1,500 stem cell lines derived from diseased cells set to aid drug development

The StemBANCC project, developed as a joint effort between the European Union and Europe’s pharmaceutical industry, is set to culture 1,500 pluripotent stem cell lines derived from the cells of diseased individuals like Alzheimer’s patients is currently planned. Using this massive database, researchers will be able to achieve much smoother and faster drug screening process in order to counter these diseases. The 50

Making brain cells from urine

Some of the human waste we flush out each day could become valuable research material – a potent source of brain cells to analyze, something extremely important for neurodegenerative diseases studies. The technique, described in Nature Methods doesn’t involve embryonic stem cells, which have serious drawbacks when transplanted such as the risk of developing tumours. Instead, the method uses ordinary

DNA not the same in every cell of the body, groundbreaking study finds

Popular scientific consensus says that DNA code is identical in every cell of our bodies. A new study from Yale University that could pose extreme far reaching consequences in the field tested a highly controversial hypothesis that claimed genetic variations are widespread through out the body. The researchers found that this claim is true. For instance, 30 percent of skin cells

Scientists grow mice from dish-cultured sperm and egg

Kyoto University researchers have produced normal, healthy mouse pups after inseminating a foster mother with eggs and sperm derived from stem cells, exclusively grown in a petri dish. This remarkable accomplishment came after last year scientists produced mouse pups from stem cell grown sperm. Their research might lead to the development of novel techniques through which infertile couples may conceive.

Scientists grow rudimentary human liver in a dish

In an extraordinary feat of science, Japanese scientists have used induced stem cells to grow into a liver-like tissue in a dish. The researchers have a long way ahead of them before they can grow livers safe for human transplants, which is the main goal, however even at its current stage, the tissue grown by the researchers can satisfy rudimentary metabolic functions