It seems like re-purposing drugs can be a gold mine for future drug development. Now, scientists have discovered that a drug used for decades in liver treatments might effectively slow down Parkinson’s disease.
Scientists have “reprogrammed” skin cells to act as neurons and then successfully implanted them into the brain of mice. After 6 months, the new nerve tissue was fully functional and there was no sign of rejection or other side effects.
Researchers have managed to take skin cells from monkeys, reverse engineer them into stem cells, and then transplant into the monkeys’ brain where they successfully became brain cells. This technique holds massive promise for treating mental degenerative diseases. The generation of induced pluripotent stem cells (iPSCs) opens up the possibility for personalized cell therapy. Using Rhesus monkeys iPSC-derived neural progenitors,
For most Parkinson’s patients, tremors associated with this devastating disease make living a normal life extremely difficult, if not impossible. Cooking, eating, even tying one’s shoelaces, basically anything that implies limb manipulation is very difficult to achieve by one’s self. A novel type of therapy developed by physicians at Oxford University, however, brings a glimmer of hope that Parkinson’s patients
A group of researchers have successfully tested a novel nanodevice treatment, in which intelligent nanoparticles selectively open and release drugs which target aging cells. The approach could render results when treating patients suffering from diseases involving tissue or cellular degeneration such as cancer, Alzheimer’s, Parkinson’s, accelerated aging disorders (progeria). It could also boosts results in the cosmetic industry, where anti-aging products are always
Be it a bacteria or a fully complex being, say a human, all living, biological organisms undergo lighting fast protein structure reassembly in response to environmnetal stimuli. For instance, receptor proteins in the sinus are stimulated by various odor molecules, basically telling the organism that there’s food nearby or it’s in the vicinity of danger (sulphur, methane, noxious fumes). By studying these mechanisms,
In what’s maybe the most startling research I’ve been granted to read about recently, scientists from South Korea at Seoul National University, home to the world’s only strictly genetic engineering curricula, have successfully created a dog that can glow in the dark. The genetically modified female beagle, named Tegon, was born in 2009 using a cloning technique which could help
While gene-therapy is still regarded as a very innovative practice, it seems like the procedure might take traction as of today when remarkable results were concluded after the first successful double-blind gene therapy for Parkinson disease. In the case of this dreadful disease, medical researchers injected patients with a a gene that codes for glutamic acid decarboxylase (GAD), an enzyme
It never ceases to amaze me how this kind of idiotic, or perhaps even intentionally wrong studies are published and accepted by the world. What am I talking about ? Well, you know those pamphlets and promotional stuff that show your brain with holes in it when you take ecstasy, or that you will get Parkinson and all that ?
Every once in a while, you hear about the hardest of problems that have really easy solutions. In numerous cases, cures have been found in most common of substances, or even foods. This time, a study led by researchers at Children’s Hospital & Research Center Oakland showed that in small concentrations, something as common as methylene blue could significantly slow