Quantcast
ZME Science
  • News
  • Environment
  • Health
  • Future
  • Space
  • Features
  • More
    • About
    • The Team
    • Advertise
    • Contribute
    • Our stance on climate change
    • Privacy Policy
    • Contact
No Result
View All Result
ZME Science

No Result
View All Result
ZME Science
No Result
View All Result
Home Health & Medicine Genetics

Childbirth can make women’s cells age faster than smoking or obesity

Scientists discovered that having children significantly shortened telomeres (genetic markers of aging).

Francesca Schiopca by Francesca Schiopca
February 26, 2018
in Genetics, Science
Reading Time: 3 mins read
A A
Share on FacebookShare on TwitterSubmit to Reddit

We all know that pregnancy and childbirth change women’s minds and bodies. A new study has found that women who give birth can age very fast, genetically speaking. But how?

Via Pixabay/marvelmozhko

Researchers collected DNA data from 1,505 different women from the US, with ages ranging from twenty to forty-four and discovered that having children significantly altered genetic markers of aging — telomeres, to be exact.

Telomeres are repetitive DNA fragments found at each end of the chromosomes, which protects them from deterioration or from fusion with neighboring chromosomes. At birth, our telomeres are long, but with each cell replication, telomeres grow shorter. Thus, telomere length decreases from birth to death and is considered a marker of aging. Shorter telomeres are correlated with outcomes like cancer, heart disease, and cognitive decline. Another cause of telomere shortening is stress,

ADVERTISEMENT

Epidemiologist Anna Pollack from George Mason University and her team analyzed data from the National Health and Nutrition Examination Survey (NHANES) – one of the largest cross-sectional studies charting the wellness of people in the US.

Sorry to interrupt, but you should really...

...Join the ZME newsletter for amazing science news, features, and exclusive scoops. More than 40,000 subscribers can't be wrong.

   

Researchers analyzed data collected between the years 1999–2002, a period in which the survey included telomere measurements, and discovered something unsettling.

Once the team had adjusted for things like age, ethnicity, education, and smoking status, they discovered that women who had given birth to at least one child had telomeres that were 4.2 percent shorter on average than those of women who had not borne children.

ADVERTISEMENT

Researchers explain that this percentage translates to around 11 years of rapid cellular aging. Compared to smoking (a cost of 4.6 years of cellular aging) and obesity (8.8 years), motherhood seems to be the champion of accelerated  DNA aging.

The study also revealed that the more children you have, the more your telomeres shrink.

“We found that women who had five or more children had even shorter telomeres compared to those who had none, and relatively shorter relative to those who had one, two, three or four, even,” Pollack told Newsweek.

The authors attributed telomere shortening to the stress accompanying having children, but they are not yet entirely sure of the cause. This study was purely observational, showing only a correlation between the two.

A 2016 study that analyzed telomere size in Mayan communities in Guatemala found that women in the community that had more surviving children had longer telomeres, suggesting that having children could actually protect women from cellular aging. Researchers believe that Mayan communities give more social support to their mothers than the US does — a great deal of stress being involved in the upbringing of the US kids.

“Anecdotally, just chatting with my friends who have children, we all do feel that having kids has aged us,” Pollack said to Newsweek. “But scientifically, this does fit with what we understand pretty well. We know that having kids is associated with a higher risk of heart disease and diabetes. And some large studies have linked telomere length to mortality risk and risks of other major diseases.”

Of course, having a child doesn’t mean you literally age 11 years. The authors write that their dataset lacked information on social factors, stress and fertility status, which may help explain these findings. With only two other previous studies regarding this matter being published, this paper‘s findings should be interpreted with caution, the authors warn.

Tags: accelerated agingagingcellular agingchildchildbirthchildrendnagiving birthhaving childrenkidkidsmotherhoodtelomeretelomeres
ShareTweetShare
Francesca Schiopca

Francesca Schiopca

ADVERTISEMENT
ADVERTISEMENT
  • News
  • Environment
  • Health
  • Future
  • Space
  • Features
  • More

© 2007-2019 ZME Science - Not exactly rocket science. All Rights Reserved.

No Result
View All Result
  • News
  • Environment
  • Health
  • Future
  • Space
  • Features
  • More
    • About
    • The Team
    • Advertise
    • Contribute
    • Our stance on climate change
    • Privacy Policy
    • Contact

© 2007-2019 ZME Science - Not exactly rocket science. All Rights Reserved.