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Japanese woman is first recipient of next-generation stem cells

A Japanese woman in her 70s is the world’s first recipient of cells derived from induced pluripotent stem cells, a technology that promises to work wonders and has the scientific community excited about the perspectives. Surgeons working on the case created the retinal tissue after reverting the patient’s own cells to ‘pluripotent’ state. If you’d like to […]

Whole organ 'grown' in animals for the first time

A whole functional organ has been successfully grown in animals for the first time; a group of Scottish researchers created a group of cells which, when transplanted into a mouse, developed into a fully functional thymus – a critical part of the immune system. The findings could lead to a revolution in organ transplant. The […]

Scientists find how lizards regenerate their tails

It’s one of the most remarkable adaptations in the animal world – growing a tail or a limb. Some lizards do it, salamanders do it, and by learning how they do it, we may soon be able to do it as well; with technology, that is. A team of researchers have discovered the genetic “recipe” for […]

Resetting the immune system back 500 million years

Researchers at the Max Planck Institute of Immunobiology and Epigenetics (MPI-IE)  re-activated the expression of an ancient gene in mice. To their surprise, the gene in question which is dormant in all mammalian species caused the mice to develop  fish-like thymus. The thymus is an organ of paramount importance to the adaptive immune system, but in […]

PMS may have evolved to disrupt infertile relationships

A brave Australian professor of molecular biology thinks he may have found out  why women get premenstrual syndrome (PMS). According to his findings, following genetic screenings, PMS has evolved as a mechanism for breaking up infertile relationships and thus increase the chance of fostering a fertile relationship in the future. Effectively, nature designed PMS to […]

Fish oil could be grown in plants

When you think about fish oil, you probably wouldn’t think of the English countryside – but that’s exactly where scientists are trying to grow it; yep, grow it! They’re using Camelina sativa plants genetically modified to produce long chain omega-3 fatty acids—the primary component of “fish oil.” Things you didn’t know about fish oil Most of the fish […]

Genetic response to starvation is passed down to at least three generations

In 1944, the Nazis caused widespread famine in Western Netherlands after they blocked food supplies. A group of pregnant women living in the Netherlands, labouring under starvation conditions imposed by a harsh winter and food embargo, gave birth to relatively small babies. When their children grew up, in relative prosperity, to have children of their own their babies were unexpectedly small.

Computer games sometimes better than medication in treating elderly depression

Computer games could be the key to treating elderly people who have been diagnosed with depression, but who aren’t responding to conventional treatment. A new study has shown that playing a certain type of computer games was more effective at reducing symptoms of depression than the “gold standard” – the antidepressant drug escitalopram. Recently, we’ve been bombarded about […]

Potential HIV-1 cure works by deleting the virus' DNA from the genome

HIV is maybe one of the most resilient and tenacious viral infections known to medical science. Unlike other infections, even if all traces of HIV are gone from the body – the virus itself – it can still resurface and infect the patient later on. That’s because HIV inserts itself permanently into the patient’s genome, […]

Mutated cat poop parasite treats cancer

Right now, I’m the happy caregiver of seven cats (five kittens. Yey!) which in most people’s books makes me socially challenged and insane. I do take special notice of my pets, and this means looking after them so they don’t get infected by parasites. Cats are typically clean animals, but when infested can spell trouble […]

Mutant worm that doesn't get drunk could help end alcoholism

An unlikely worm might help millions of people fighting alcohol addiction. No, you won’t find it in tequila, but in the labs of neuroscientists at University of Texas at Austin who have engineered  Caenorhabditis elegans – one of the most popular animal models in science – to become insensitive to alcohol intoxication. The findings, if replicated on […]

Friends are family: study shows we share more genes with friends than strangers

We often cherish our closest friends as if they were family. Well, this isn’t actually too far from the truth, considering a new study from the University of California, San Diego, and Yale University found friends who aren’t biologically related resemble each other genetically. In fact, on average friends are as “related” as fourth cousins […]

Chemical switch found in Alzheimer's and stroke victims' brains kills neurons

Researchers at the Sanford-Burnham Medical Research Institute (Sanford-Burnham) have found a chemical switch that both regulates the generation of new neurons from neural stem cells and the survival of existing nerve cells in the brain. Postmortem examination of the brains of Alzheimer’s patients and stroke victims found the switch that shuts off the signals was […]

Unique gene passed by extinct human species makes Tibetans superhuman

Advancements in genetic sequencing has allowed genomic research to flourish. DNA sequencing is now much faster, cheaper and accurate than ever before, and we’re only now beginning to reap the rewards. It’s the first step to a complete understanding of our bodies. The Human Genome Project, once finally completed, mapped and identified all the genes of […]

Malaria-carrying mosquitoes manipulated only to breed males, thus wiping whole populations

According to latest estimates by the World Health Organisation, over 3.4 billion people are at risk from contracting malaria and an estimated 627,000 people die each year from the disease. Thanks to the painstaking efforts of leading researchers in the field, however, much progress has been made in curbing down on malaria. Since 2000, increased […]

Scientists genetically screen alleged Yeti samples, find they're from known mammals instead

One of the most popular urban myths speaks of Bigfoot – an 8-foot tall creature, covered in thick, dark hair. The creature, also known as sasquatch or Yeti (the Asian counterpart) has spurred the imagination of countless people, some of whom went a step farther to report actual sightings of the elusive beast. If you […]

Leukemia drug found to dramatically boost immune system

A class of drugs currently used to treat leukemia has been found to have some severe side effects – positive ones, that is. The drug was found to drastically boosting immune responses against many different cancers, reports a new study. The drug class is referred to as p110´ inhibitors. Recently, it has been used with […]

Three parent babies: possible in two years

Every baby has a mother and a father, right? As in one of each. Well, that may change soon, according to a new UK report. In February, the FDA announced it was considering 3-parent embryos; while this would be an excellent way to stop some deadly diseases, it also raises many ethical questions, and the reaction (as […]

Shorter men live longer, study shows

While being taller has been correlated with success in life, being short also has its perks: a team of researchers has shown that shorter men tend to live longer. “We split people into two groups — those that were 5-foot-2 and shorter, and 5-4 and taller,” said Dr. Bradley Willcox, one of the investigators for […]

Scientists engineer first living organism with unnatural DNA

The entire living world is “written” with just four DNA bases: A = adenine C = cytosine G = guanine T = thymine However, for the first time, researchers have now created a living cell with an added pair of DNA “letters,” or bases, not found in nature – the DNA alphabet just got some new letters! “Life on Earth […]

Bone marrow-on-a-chip could remove bone marrow animal testing

A new “organ on a chip” has been developed by Harvard researchers, reproducing the structure, functions, and cellular make-up of bone marrow, a complex tissue that until now, could only be studied on living animals. Bone marrow is one of the more complex and fragile parts of the human body – many drugs and toxic elements […]

How humans and squids came to have similar eyes

Humans and squids are not exactly close relatives – as a matter of fact, we’re really different from squids, so how come we came to have surprisingly similar eyes? The answer, as usually, is in our genes. Eyes are complicated things – and like all organs, they rely on many genes working together, keeping everything […]

Sperm RNA carries marks of trauma

Scientists have shown that trauma can leave epigenetic marks – chemical changes that affect how DNA is expressed without altering its sequence. Basically, your traumatic experiences genetically affect your offspring. Scientists have recently focused on the long term after effects of trauma, finding them to be numerous and diverse. The offspring of traumatized people are at […]

Harmless bacteria turned deadly just 30 years ago - now, it kills 500.000 every year

It’s a truly terrifying story, and a truly terrifying disease. The flesh-eating culprit in question is called GAS, or Group A β-hemolytic streptococcus, a highly infective bacteria. Apart from causing the flesh-eating disease necrotizing fasciitis, GAS is also responsible for a range of less harmful infections. But like most bacteria, it was harmless at one point in its […]

Lions' origin revealed by genetic analysis

The origin and evolutionary history of modern lions has been revealed through genetic analysis. This recent study suggests that the lions’ most recent common ancestor lived around 124,000 years ago. A fallen king Modern lions evolved in two different groups – one of them currently lives in Eastern and Southern Africa, the other includes lions […]

Aging successfully reversed in mice - human trials to start next

As incredible as it may sound, scientists have successfully reversed the aging process in mice, according to a new study published in Cell. Reversing aging, a real possibility? Many of the chronic diseases that exist in older adults constitute a highly significant social and economic burden to the community; if you think about it, eliminating […]

Yeast chromosome engineered from scratch: creating cretures in a lab

In a huge breakthrough in synthetic biology, scientists at Johns Hopkins University have engineered from scratch a yeast chromosome. This is the first time scientists have been able to assemble a chromosome from a creature as complicated as a yeast, namely a prokaryrite. The implications of this research are far and wide. For one, the […]

Sea anemone is genetically half animal, half plant

Sea anemones are remarkable creatures. They are a group of water-dwelling, predatory animals, but if you look at them, they look like plants more than animals. Now, a team of evolutionary biologists from the University of Vienna has discovered that sea anemones display a remarkable genome, featuring a complexity of regulatory elements similar to that of fruit […]

Large clinical study shows staggering 88% remission rate in leukemia patients

The largest clinical study ever conducted to date of patients with advanced leukemia found that an incredible 88% of patients entered remission after being treated with genetically modified versions of their own immune cells. It’s like the medicine of tomorrow – today; and it’s super effective. “These extraordinary results demonstrate that cell therapy is a […]

Human brain artificially created in laboratory

Human embryonic stem cells can be induced into forming a developing brain tissue. The brain development process represents one of the most specific processes; during it, neuroepithelium, formed as a flat sheet by the nervous system, grows on the exterior layer of the embryo, after which it folds in to create a neural tube giving […]

Chimeric organ harvesting: growing human organs inside pigs

Sure to raise a slew of controversy and debate, researchers in Japan are currently investigating the possibility of growing human organs, like kidneys, livers or even hearts, inside pigs. A real life chimeric tale, as if spawned from the Island of Dr. Moreau. The challenges are numerous though, both technical (we’re talking about growing human […]

Remembering faces is influenced by genetics. Face recognition gene found

Some people just have the knack of remembering the face of everyone they’ve met in their lives, while others, on the opposite end of the spectrum, have a difficult time  recognizing who they met yesterday. Now, researchers at Emory have identified the oxytocin receptor, a gene known to influence mother-infant bonding and pair bonding in monogamous […]

The uniqueness of smell: no two people smell the same

Just like taste, it’s really common for people not to agree on how pleasant or fowl a scent may be. You might find the meal you just cooked to have a pleasant odor or you might have bought a perfume you thought smelled divine, only for some other person to disagree and express a distaste. […]

Single protein plays key role in almost all lung diseases

From the common cold to pneumonia and potentially life threatening lung diseases: a single protein was found to play a key role. Now, an international team of researchers has finally zeroed in it. The key protein is called MUC5B – it is one of the two proteins found in the mucus that normally and helpfully […]

A gene mutation for excessive alcohol drinking found

  Mice in the control group refused to drink alcohol When a certain gene was deactivated, they started preferring alcohol over water Researchers stress that human alcoholism depends much more on environmental and personal factors Researchers have discovered a gene that regulates alcohol consumption; when this genes becomes faulty, it makes humans more prone to […]

Promiscuous female mice breed sexier male offspring. Research may help conservation efforts

University of Utah researchers found that female mice that live in a competitive social environment and choose to mate casually with multiple partners give birth to males who are much more attractive to female mice, at the cost of a dramatic cut in life expectancy however. You only have one life, says the sexy male […]

Going to the root of cancer fatality: metastasis

It’s not the cancer tumor itself that kills people, but rather the spread of cancer cells is what ultimately may bring the killing blow to patients. This is called metastasis, and oddly enough not nearly enough is known about how it works. University of Minnesota researchers have devised a pathological method for doctors to assess whether […]

Biopatch stimulates bone growth via DNA instructions

You’ll be pretty impressed by this novel research. Scientists at  University of Iowa have developed an ingenious biopatch which expels nanoparticles containing DNA that instructs cells to turn into bone. Practically, you just apply this patch over a damaged area that needs reconstruction, dental surgery site or congenital bone defect and the genes do the rest of […]

Study Finds Natural Compound Can Be Used for 3-D Printing of Medical Implants

Researchers from North Carolina State University, the University of North Carolina at Chapel Hill and Laser Zentrum Hannover have worked together to discover a natural compound which can be used in the 3D printing process of creating medical implants out of non-toxic polymers. The compound goes by the name riboflavin, but is better known as […]

Origin of life a fluke? Study suggests more's at play than just randomness

One of the greatest mysteries scientists have been trying to reveal is how inanimate chemicals  joined  to produce life. It’s definitely one of the biggest questions scientists are trying to answer, and the challenges are numerous since it’s very difficult to appreciate what the exact conditions necessary for this to happen were billions of years […]

New anti-baldness treatment may grow new hair using patient's own cells

Anti-baldness treatments available today work by stimulating hair follicle health or slow down hair loss. There is no available method that promotes the growth of new hair, however. You might have heard of hair transplants, but this typically involves transplanting hair from another area of the hair, like the back of the head, to the […]

Faeces-filled pill stops gut infection

Faeces based treatment halts the advance of Clostridium difficile bacteria, but a commercial treatment is still far away. Using a faeces in the treatment of the gut infections and diarrhea is not a new idea, though it’s still in its initial stages. In 2010, we told you about a woman who had a life threatening […]

Nobel Prize in Physiology or Medicine 2013 Awarded

Has it already been a year? It’s Nobel Prize season once again, and the first award has been given in “Physiology or Medicine“. James E Rothman, Randy W Schekman and Thomas C Südhof took the prize for their work on the mechanism that controls the transport of membrane-bound parcels or ‘vesicles’ through cells. The American […]

Scientists discover on/off switch for eating

After they identified precise groups of cells in mice brain that induce eating and others that curb it, a team of researchers caused full mice to continue eating and hungry mice to stop eating simply by stimulating one of these areas. Their findings could aid in the development of novel drugs that target eating disorders […]

New Imaging Technique Reveals the True Form of Chromosomes

The X-Shape in which we usually see chromosomes depicted in is only a snapshot of their real complexity – a new method for visualizing them showed. A joint project involving the Babraham Institute, the University of Cambridge and the Weizmann Institute has produced the most beautiful and accurate models of chromosomes available up to date. […]

How a girl that doesn't feel pain at all might help create the painkillers of tomorrow

Some people are born with the innate ability, or better said disability, of not feeling pain – whatsoever. It’s not that they can’t feel anything, quite on the contrary – they still have a sense of texture, they feel pressure, they can feel a hug or handshake just like anyone, they experience warmth or coldness […]

Convergent evolution in bats and dolphins driven by same genes

It’s amazing how two different animals from two completely different environments evolve some identical physical features. Take bats and dolphins for instance. Both of them use a complex system that produces, receives and process ultrasonic sound waves in order to identify visually hidden objects, track down prey or navigate through obstacles better – typically this […]

Biologists discover new mutations which lead to asexuality

A team of evolutionary biologists at Indiana University has shown for the first time that asexual lineages of a species are doomed not necessarily from a long, slow accumulation of new mutations, but rather from fast gene conversions which unmask preexisting genetic mutations. The groundbreaking research started with the sequencing of the entire genomes of […]

Gene key in neuron generation discovered

Scientists have discovered an atypical gene that is thought to be crucial for the generation of new neurons in the brain, a process called neurogenesis. The discovery and further study of the gene might help scientists better understand how neurodegenerative diseases such as Alzheimer’s affect the brain and, in term, how to address them. New […]

Down Syndrome's extra chromosome shut down in lab cells

The insertion of one gene can shut down the extra chromosome which causes Down Syndrome, according to a study published today in Nature. A dreadful disease Down Syndrome (DS), also known as trisomy 21, is a genetic disorder caused by the presence of all or part of a third copy of chromosome 21. It’s the […]