homehome Home chatchat Notifications


Why researchers are confident that we'll (eventually) have a COVID-19 vaccine

It could be 12 months or even more, but we will have a vaccine.

Mihai Andrei
March 31, 2020 @ 11:51 pm

share Share

It’s not false hope. It will be a year, a year and a half, or potentially even more, but there are strong reasons to believe that we will ultimately have a vaccine for COVID-19.

Comparison to the common cold

At first glance, it seems weird. We’re familiar with coronaviruses in general, we know they cause some common colds, we don’t have a vaccine for the common cold, so why would we have one for COVID-19?

While some coronaviruses do indeed cause the common cold, they’re far from the only virus to do so. The common cold is not a single virus, it is a term we use for infections associated with approximately 200 different viruses (noroviruses, rhinoviruses, etc). Devising a vaccine that works for all these different viruses, as well as their genetic variations and the different strains that emerge from year to year, is extremely challenging.

Meanwhile, SARS-CoV-2, the virus that causes COVID-19, is a single virus — and one which, according to recent studies, mutates at a relatively slow rate. This is encouraging because it checks all the boxes for a vaccine candidate.

Comparison with the influenza

Hopefully, we’re all done with comparing COVID-19 to influenza, but for the purpose of a vaccine, there are also valuable lessons.

We have an influenza vaccine — well, several, actually. There are multiple influenza strains and every flu season is different, in part because there are several influenza strains — but also because they mutate rapidly.

Unlike SARS-CoV-2, flu strains exhibit a high variability, which is why no flu vaccine is guaranteed 100% effective. We also have to make the flu shot yearly because of this reason, and also because antibodies generated by the vaccine can wane over time. As SARS-CoV-2 mutates slower, there’s a good chance (but not a guarantee) that the vaccine could be effective for a longer time.

Probably not before 2021

But while there is plenty of reason to be optimistic in the long run, it’s unlikely that a vaccine can be developed within 6 months. The likely time frame that we’re looking at is 12-18 months — though, in truth, it’s been about a month since we heard that timeline, so let’s be optimistic and say it’s 11-17 months. Of course, there are few guarantees regarding the timeline.

It’s not entirely unlikely that a vaccine is developed more quickly. Human trials are imminent (some have already started), and there is an unprecedented impetus to develop vaccines against the disease. But ensuring that a vaccine is safe and effective takes a long time. Most vaccinologists are even wary of the 12 months timeframe, suggesting that a year and a half is probably more realistic.

Then, even after it is demonstrated, the vaccine needs to be mass-produced and distributed, which would take enormous resources. We will, almost certainly, get there. But it will take quite some time to do so.

share Share

Forget the wild-haired savages. Here's what Vikings really looked like

Hollywood has gravely distorted our image.

Is a Plant-Based Diet Really Healthy for Your Dog? This Study Has Surprising Findings

You may need to revisit your dog's diet.

Who Invented Russian Roulette? How a 1937 Short Story Sparked the Deadliest "Game" in Pop Culture

Russian Roulette is deadly game that likely spawned from a work of fiction.

What Do Ancient Egyptian Mummies Smell Like? "Woody", "Spicy" and Even "Sweet"

Scientists used an 'electronic nose' (and good old biological sniffers) to reveal the scents of ancient mummies.

A Massive Seaweed Belt Stretching from Africa to the Caribbean is Changing The Ocean

The Great Atlantic Sargassum Belt hit a record 37.5 million tons this May

Stone Age Atlantis: 8,500-Year-Old Settlements Discovered Beneath Danish Seas

Archaeologists took a deep dive into the Bay of Aarhus to trace how Stone Age people adapted to rising waters.

Researchers Turned WiFi into a Medical Tool That Reads Your Pulse With Near Perfect Accuracy

Forget health trackers, the Wi-Fi in your living room may soon monitor your heartbeat.

Popular RVs in the US are built with wood from destroyed orangutan rainforest: Investigation

The RV industry’s hidden cost is orangutan habitat loss in Indonesia.

The Evolution of the Human Brain Itself May Explain Why Autism is so Common

Scientists uncover how human brain evolution boosted neurodiversity — and vulnerability to autism.

A Light-Based AI Can Generate Images Using Almost No Energy

The future of AI art might be powered by lasers instead of GPUs.