homehome Home chatchat Notifications


Sperm gene discovery might lead to male birth control

A male birth control might not be so far away as most people thought – especially as Scottish scientists have uncovered a key gene essential for sperm development. The gene, which for some reason was named called Katnal1, is critical for sperm production, as it enables the little guys to mature; thus, if a pill […]

Mihai Andrei
May 25, 2012 @ 10:51 am

share Share

A male birth control might not be so far away as most people thought – especially as Scottish scientists have uncovered a key gene essential for sperm development.

The gene, which for some reason was named called Katnal1, is critical for sperm production, as it enables the little guys to mature; thus, if a pill could be created to regulate this gene, sperm production would be halted.

If we can find a way to target this gene in the testes, we could potentially develop a non-hormonal contraceptive,” study author Dr. Lee Smith, a reader in genetic endocrinology at the Medical Research Council Center for Reproductive Health at the University of Edinburgh in Scotland, said in a news release.

The other, hormonal, male birth control has numerous unwanted side effects due to the modification of testosterone production, including but not limited to mood swings, acne, irritability etc, so this new method, with no other visible side effects in sight could be perfect for many who want something else than condoms and vasectomies. But, of course, no visible side effects in sight so far. Also, this proposed method would carry another significant advantage.

“The important thing is that the effects of such a drug would be reversible because Katnal1 only affects sperm cells in the later stages of development, so it would not hinder the early stages of sperm production and the overall ability to produce sperm,” he said.

Aside for using this research as a contraceptive method, it could also shed some light in important matters.

“The gene described by the research group in Edinburgh sounds like an exciting new possible target for a new male contraceptive, but it may also shed light on why some men are sub-fertile and why their sperm does not work properly,” Pacey said.

share Share

A small, portable test could revolutionize how we diagnose Alzheimer's

A passive EEG scan could spot memory loss before symptoms begin to show.

2.2 Million Fat-Removal Surgeries a Year: What's Behind the Body Contouring Boom

From liposuction to cryolipolysis, fat-removal is now one of the most common cosmetic choices worldwide.

Labiaplasty Is the Fastest-Growing Cosmetic Surgery Worldwide — And It’s Not Just About Looks

Once a taboo subject, vaginal rejuvenation is now part of a broader conversation about women’s intimate wellness.

Ultra-Processed Foods Made Healthy Young Men Gain Fat and Lose Sperm Quality in Just Three Weeks

Processed foods harmed hormones and fertility markers even with identical calories.

Could AI and venom help us fight antibiotic resistance?

Scientists used AI to mine animal venom for potent new antibiotics.

Scientists Reprogram Blood Cells to Prevent Alzheimer’s and Fight Aging In the Brain

In a promising new study, modified young immune cells improved brain performance in older mice.

America’s Sex Ed System Is An Anti-Science Nightmare

Only 37% of US states require sex ed to be medically accurate.

Doctors with More Patient Complaints Also More Likely to Take Industry Money, Study Finds

There seems to be a concerning link between patient complaints and industry payouts.

A Daily Pill Helped Obesity Patients Lose Over 10 Kilograms in Major Trial, But Injectibles Are Still Slightly Better

The pill matches injections in effectiveness, offering a needle-free option for millions

Scientists Transplant Pig Lung Into Human for the First Time. It Worked for Nine Days

Genetically engineered lung functioned for nine days, marking a tentative step for xenotransplantation.