Amyloids are insoluble fibrous protein aggregates sharing specific structural traits. They arise from at least 18 inappropriately folded versions of proteins and polypeptides present naturally in the body. These misfolded structures alter their proper configuration such that they erroneously interact with one another or other cell components forming insoluble fibrils. They have been associated with the pathology of more than 20 serious human diseases in that, abnormal accumulation of amyloid fibrils in organs may lead to amyloidosis, and may play a role in various neurodegenerative disorders.
Researchers report that after testing on lab mice an FDA-approved drug, used as treatment for skin cancer, that significant improvements in cognitive recovery were signaled, shinning a new ray of hope for Alzheimer patients. Neuroscientists Case Western Reserve University School of Medicine discovered that bexarotene, a skin cancer drug, remarkably also appears to reverse cognitive [...]